DNA demethylating agents suppress preclinical models of synovial sarcoma

Hasegawa N*, Benabdallah NS*, Smith-Fry K, Li L, McCollum S, Li J, Jones CA, Wagner L, Dalal V, Golde V, Pejkovska A, Carroll L, Haldar M, Pollack SM, Lowe SW, Nielsen TO, Banito A#, Jones KB#.

*Co-first authors, # Co-corresponding authors

The journal of Clinical Investigation

2025

Aberrant gene activation in synovial sarcoma relies on SSX specificity and increased PRC1.1 stability

Benabdallah NS, Dalal V, Scott RW, Marcous M, Sotiriou A, Kommoss FKF, Pejkovska A, Gaspar L, Wagner L, Sánchez-Rivera FJ, Ta M, Thornton S, Nielsen TO, Underhill TM, Banito A.

Nature Structural & Molecular Biology

2023

The bromodomain inhibitor JQ1 is a molecular glue targeting centromeres

Corless S, Singh NP, Benabdallah NS, Boehm J, Simon AM, Dolejs V, Anders S, Banito A, Erhardt S.

BioRxiv

2023

Decreased Enhancer-Promoter Proximity Accompanying Enhancer Activation

Benabdallah NS, Williamson I, Illingworth RS, Kane L, Boyle S, Sengupta D, Grimes GR, Therizols P, Bickmore WA.

Molecular Cell

2019

SBE6: a novel long-range enhancer involved in driving sonic hedgehog expression in neural progenitor cells

Benabdallah NS, Gautier P, Hekimoglu-Balkan B, Lettice LA, Bhatia S, Bickmore WA.

Open Biology

2016

Regulatory Domains and Their Mechanisms

Benabdallah NS, Bickmore WA.

Cold Spring Harbor Symposia on Quantitative Biology

2015